Pyridin-3-amine, 4,6-dichloro- - Names and Identifiers
Name | 4,6-Dichloropyridin-3-amine
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Synonyms | 4,6-Dichloro-3-pyridinamine 4,6-DICHLOROPYRIDIN-3-AMINE 4,6-Dichloropyridin-3-amine 5-AMINO-2,4-DICHLOROPYRIDINE 2,4-Dichloro-5-aMinopyridine 2,4-dichloro-5-aminopyridine 3-pyridinamine, 4,6-dichloro- 3-Pyridinamine, 4,6-dichloro- 4,6-Dichloro-Pyridin-3-Ylamine 4,6-DICHLORO-PYRIDIN-3-YLAMINE Pyridin-3-amine, 4,6-dichloro- Pyridine,5-amino-2,4-dichloro- (7CI,8CI)
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CAS | 7321-93-9
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InChI | InChI=1/C5H4Cl2N2/c6-3-1-5(7)9-2-4(3)8/h1-2H,8H2 |
Pyridin-3-amine, 4,6-dichloro- - Physico-chemical Properties
Molecular Formula | C5H4Cl2N2
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Molar Mass | 163 |
Density | 1.497±0.06 g/cm3(Predicted) |
Melting Point | 80-81 °C(Solv: ligroine (8032-32-4)) |
Boling Point | 290.8±35.0 °C(Predicted) |
Flash Point | 129.7°C |
Vapor Presure | 0.00202mmHg at 25°C |
Appearance | Powder |
Color | Pale brown |
pKa | 0.72±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.622 |
Pyridin-3-amine, 4,6-dichloro- - Risk and Safety
UN IDs | UN2811 |
Hazard Class | 6.1 |
Pyridin-3-amine, 4,6-dichloro- - Introduction
4,6-Dichloropyridin-3-amine is an organic compound with the chemical formula C5H4Cl2N. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 4,6-Dichloropyridin-3-amine is a colorless or light yellow crystal or crystalline powder.
-Solubility: It is soluble in many organic solvents, such as chloroform, ether and dichloromethane, but has low solubility in water.
-Melting point: Its melting point range is 92-96°C.
-Molecular weight: Its relative molecular mass is 158.00.
Use:
- 4,6-Dichloropyridin-3-amine is usually used as an intermediate in organic synthesis and can be used to synthesize various organic compounds.
-It can also be used as a synthetic raw material in the pharmaceutical field for the preparation of drugs and biologically active molecules.
-Due to its unique chemical structure, it can also be used as a reagent and ligand for coordination chemical reactions.
Preparation Method:
The preparation method of-4,6-Dichloropyridin-3-amine usually involves a substitution reaction on the pyridine ring.
-A common preparation method is to react 3-bromopyridine with copper chloride, and then reduce it with sebacic acid to obtain 4,6-Dichloropyridin-3-amine.
Safety Information:
- 4,6-Dichloropyridin-3-amine is an organic compound, so it has certain toxicity and irritation. Pay attention to protective measures during operation, including wearing chemical protective glasses, gloves and laboratory coats.
-During storage, the compound should be kept sealed in a cool, dry place, away from fire and oxidizing agents.
-Avoid contact with strong oxidants, strong acids and strong bases during use to avoid dangerous chemical reactions.
-When handling and disposing of 4,6-Dichloropyridin-3-amine, local environmental protection regulations should be followed.
Last Update:2024-04-09 21:04:16